Publications 2022

Azithromycin promotes relapse by disrupting immune and metabolic networks after allogeneic stem cell transplantation.
Nicolas Vallet, Sophie Le Grand, Louise Bondeelle, Benedicte Hoareau, Aurelien Corneau, Delphine Bouteiller, Simon Tournier, Lucille Lew-Derivry, Armelle Bohineust, Marie Tourret, Delphine Gibert, Ethan Mayeur, Raphaël A Itzykson, Kim Pacchiardi, Brian Ingram, Stephane Cassonnet, Patricia Lepage, Régis Peffault de Latour, Gérard Socie, Anne Bergeron, David Michonneau.
Blood. 2022 Aug 19:blood.2022016926. doi: 10.1182/blood.2022016926. Online ahead of print.

Immune landscape after allo-HSCT: TIGIT and CD161-expressing CD4 T cells are associated with subsequent leukemia relapse.
Viviane Gournay, Nicolas Vallet, Vivien Peux, Kristi Vera, Jennifer Bordenave, Marion Lambert, Aurelien Corneau, David Michonneau, Régis Peffault de Latour, Sophie Caillat-Zucman, Gerard Socié, Mathieu F Chevalier.
Blood. 2022 Jul 12;blood.2022015522. doi: 10.1182/blood.2022015522. Online ahead of print.

The AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts.
Priyanka Fernandes, Manon Loubens, Rémi Le Borgne, Carine Marinach, Beatrice Ardin, Sylvie Briquet, Laetitia Vincensini, Soumia Hamada, Bénédicte Hoareau-Coudert, Jean-Marc Verbavatz, Allon Weiner, Olivier Silvie.
PLOS Pathogen June 22, 2022. doi: 10.1371/journal.ppat.1010643.

Platelet-Derived Growth Factor Receptor Type α Activation Drives Pulmonary Vascular Remodeling Via Progenitor Cell Proliferation and Induces Pulmonary Hypertension.
Julien Solinc, Jessica Raimbault-Machado, France Dierick, Lamiaa El Bernoussi, Ly Tu, Raphaël Thuillet, Nathalie Mougenot, Bénédicte Hoareau-Coudert, Virginie Monceau, Catherine Pavoine, Fabrice Atassi, David Sassoon, Giovanna Marazzi, Richard P Harvey, Peter Schofield, Daniel Christ, Marc Humbert, Christophe Guignabert, Florent Soubrier, Sophie Nadaud.

J Am Heart Assoc. 2022 Apr 5;11(7):e023021. doi: 10.1161/JAHA.121.023021. Epub 2022 Mar 29.

Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis.
Lin Lei, Alix Bruneau, Haquima El Mourabit, Justine Guégan, Trine Folseraas, Sara Lemoinne, Tom Hemming Karlsen, Bénédicte Hoareau, Romain Morichon, Ester Gonzalez-Sanchez, Claire Goumard, Vlad Ratziu, Pierre Charbord, Jérémie Gautheron, Frank Tacke, Thierry Jaffredo, Axelle Cadoret, Chantal Housset.

Hepatology. 2022 Mar 12. doi: 10.1002/hep.32456. Online ahead of print.

A negative feedback loop between fibroadipogenic progenitors and muscle fibres involving endothelin promotes human muscle fibrosis.
Mona Bensalah, Laura Muraine, Alexis Boulinguiez, Lorenzo Giordani, Victorine Albert, Victor Ythier, Jamila Dhiab, Alison Oliver, Valentine Hanique, Teresa Gidaro, Sophie Perié, Jean Lacau St-Guily, Aurélien Corneau, Gillian Butler-Browne, Anne Bigot, Vincent Mouly, Elisa Negroni, Capucine Trollet.

J Cachexia Sarcopenia Muscle. 2022 Mar 22. doi: 10.1002/jcsm.12974. Online ahead of print.

Operational tolerance after hematopoietic stem cell transplantation is characterized by distinct transcriptional, phenotypic, and metabolic signatures.
Laetitia Dubouchet, Helena Todorov, Ruth Seurinck, Nicolas Vallet, Sofie Van Gassen, Aurélien Corneau, Catherine Blanc, Habib Zouali, Anne Boland, Jean-François Deleuze, Brian Ingram, Regis Peffault de Latour, Yvan Saeys, Gérard Socié, David Michonneau.

Sci Transl Med. 2022 Feb 23;14(633):eabg3083. doi: 10.1126/scitranslmed.abg3083. Epub 2022 Feb 23.

Two New Neutrophil Subsets Define a Discriminating Sepsis Signature.
Aïda Meghraoui-Kheddar, Benjamin G Chousterman, Noëlline Guillou, Sierra M Barone, Samuel Granjeaud, Helene Vallet, Aurélien Corneau, Karim Guessous, Charles de Roquetaillade, Alexandre Boissonnas, Jonathan M Irish, Christophe Combadière.

Am J Respir Crit Care Med. 2022 Jan 1;205(1):46-59. doi: 10.1164/rccm.202104-1027OC.

Naive and memory CD4 + T cell subsets can contribute to the generation of human Tfh cells.
Raphaël Jeger-Madiot, Romain Vaineau, Maud Heredia, Nicolas Tchitchek, Lisa Bertrand, Mathias Pereira, Océane Konza, Bruno Gouritin, Bénédicte Hoareau-Coudert, Aurélien Corneau, Catherine Blanc, Eric Savier, Pierre Buffet, Adrien Six, David Klatzmann, Arnaud Moris, Stéphanie Graff-Dubois.

iScience. 2021 Dec 3;25(1):103566. doi: 10.1016/j.isci.2021.103566. eCollection 2022 Jan 21.